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KMID : 1138520090120030073
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Journal of Pharmacopuncture
2009 Volume.12 No. 3 p.73 ~ p.79
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The Experimental Study on Anti-inflammation and Anti-oxidation of GaeYongHwan
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Seo Hyeong-Sik
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Abstract
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Objectives: This study was performed to investigate the anti-inflammatory and anti-oxidantic effects of GaeYongHwan(GYH) extract which has been used for patients with acnes.
Methods: Anti-inflammatory and anti-oxidantic effects of GYH extract were tested in terms of inhibitory ability of Nitric oxide(NO) production, 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging activity and anti-bacterial effects against Propionibacterium acnes(P. acnes).
Results: 1. All GYH treated groups did not show cytotoxicity. 2. Treatment with of GYH extract lowered production levels of NO significantly compared to non-treated control or normal. 3. All of GYH treated groups did not show DPPH free radical scavenging activities. 4. All of GYH treated groups did not show anti-baterial action against P. acnes.
Conclusions: These results imply that GYH extract has anti-inflammatory effect to treat acnes.
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KEYWORD
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GaeYongHwan, anti-inflammation, anti-oxidation, NO, DPPH, Propionibacterium acnes
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